First railroad that will run west of the Mississippi is incorporated
The Pacific Railroad of Missouri is incorporated in St. Louis. It will become the first railroad to run west of the Mississippi River but will not have its inaugural run until December 23, 1852, over a five mile stretch west from St. Louis. (By John Osborne)
Joseph Nathan Kane, ed., Famous First Facts (New York: H.W. Wilson Company, 1981), 533.