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At Colón in the Panama, an exploding British cargo of nitro-glycerin devastates the port and kills fifty

Damage to docks and ships following explosion, Aspinwall, Panama, April 3, 1866, artist's impression
04/03/1866
Aspinwall, now Colón, Panama was the western terminus of the short journey across the Isthmus to the Pacific.  At around 7 a.m., the cargo of seventy cases of nitro-glycerine, together with percussion caps, exploded aboard the British freighter European as it was moored at the docks.  The ship was a total loss and extensive damage was also done to port installations. More than fifty people were killed.  (By John Osborne)
Source Citation: 
"Explosion at Aspinwall," Harper's Weekly Magazine, May 5, 1866, p. 285.