| Foreign |
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King Victor-Emmanuel of Piedmont-Sardinia explains the transfer of Nice and Savoy to France |
| Religion/Philosophy |
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Palm Sunday |
| Lawmaking/Litigating |
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Virginia State legislature finishes its 1859-1860 session |
| Campaigns/Elections |
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Republicans sweep state elections in Connecticut |
| Campaigns/Elections |
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Arkansas Democratic Convention meets in Little Rock |
| US/the World |
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In Arizona, an unauthorized convention meets to form a provisional government |
| Foreign |
|
Carlist forces land in Catalonia and declare the pretender Don Carlos as rightful King of Spain |
| Foreign |
|
Pretoria becomes capital of the South African Republic |
| Business/Industry |
|
The Pony Express begins its first run |
| Lawmaking/Litigating |
|
Local officials foil U.S. Senate attempt to arrest Frank Sanborn for failure to appear to testify on Harpers Ferry |
| Campaigns/Elections |
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Conservative Republican defeats the official Republican nominee in race for Rhode Island governor |
| Education/Culture |
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In England, George Eliot publishes her new novel |
| Foreign |
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Rebellion in Sicily against the Bourbon throne breaks out in Palermo |
| Slavery/Abolition |
|
Book-burning takes place in South Carolina during trial of man for circulating anti-slavery literature |
| Personal |
|
Edward Warren appointed professor of medicine at University of Maryland Medical School |
| US/the World |
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Count Cavour, prime minister of Piedmont-Sardinia, assures Switzerland over the transfer of Nice to France |
| Education/Culture |
|
In Boston, Henry Longfellow begins to write his famous poem, "Paul Revere's Ride" |
| US/the World |
|
The first Japanese diplomatic mission to the United States departs San Francisco for Panama |
| Personal |
|
W.K. Kellogg born in Battle Creek, Michigan |
| Religion/Philosophy |
|
Passover begins |
| Foreign |
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Plans for the plebiscite on the transfer of Nice and Savoy from Piedmont-Sardinia to France are published |
| Business/Industry |
|
The eastward and westward riders of the first run of the Pony Express cross paths somewhere in Utah |
| Crime/Disasters |
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Heavy rains cause flooding and damage in Pennsylvania and Ohio |
| Religion/Philosophy |
|
Easter Sunday |
| Crime/Disasters |
|
Earthquake strikes Haiti west of Port Au Prince |
| Science/Technology |
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In Paris, French inventor Edouard-Leon Scott de Martinville makes the first known recording of a human voice |
| Campaigns/Elections |
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Missouri Democratic Party Convention meets in Jefferson City |
| Slavery/Abolition |
|
In Virginia, Richmond police raid secret meeting of African-American group called "The Sons of Ham" |
| US/the World |
|
Switzerland once again protests the transfer of Nice and Savoy from Piedmont-Sardinia to France |
| Lawmaking/Litigating |
|
House of Representatives passes the Kansas Statehood Bill and sends it to the Senate |