| Foreign |
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Piedmont-Sardinia annexes Emilia as the unification of Italy increases pace |
| Personal |
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William H. Bissell becomes the first Illinois governor to die in office |
| US/the World |
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First Japanese diplomatic mission to the United States departs Hawaii for San Francisco |
| Crime/Disasters |
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Large boiler explosion in Detroit, Michigan results remarkably in no serious injuries |
| Personal |
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William Jennings Bryan born in Marion County, Illinois |
| Lawmaking/Litigating |
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Lieutenant-Governor Wood sworn in as Governor of Illinois after the death of William Bissell |
| Science/Technology |
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First day of Spring |
| Lawmaking/Litigating |
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United States signs extradition treaty with Sweden and Norway |
| Foreign |
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Piedmont-Sardinia annexes Tuscany as the unification of Italy increases pace |
| Foreign |
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Spanish win crushing victory over Moroccan forces |
| Religion/Philosophy |
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The Muslim feast of Ramadan begins |
| Business/Industry |
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Clipper ship sails from New York to San Francisco in record time |
| US/the World |
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Pro-Western Japanese leader assassinated |
| US/the World |
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The treaty annexing Savoy and Nice is signed in Turin |
| Foreign |
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From Germany, the Grand Duke of Tuscany protests the annexation of his province |
| Foreign |
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Spanish force Moroccan authorities to accept an armistice and begin peace negotiations |
| Religion/Philosophy |
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Pope Pius IX decrees excommunication for "sinful insurrection" in the Papal States during 1859 |
| Battles/Soldiers |
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First railroad track ever laid in Kansas put down |
| Science/Technology |
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The corkscrew receives its first United States patent |
| Campaigns/Elections |
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Constitutional Union Party begins its presidential campaign in Boston |
| Slavery/Abolition |
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Failed rescue in Philadelphia of a Virginia fugitive being returned to slavery |
| Campaigns/Elections |
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Kansas Democrats choose Stephen Douglas as their candidate for President |
| Crime/Disasters |
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Another New York City tenement fire kills two women and eight children |
| Slavery/Abolition |
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Daniel Worth convicted of selling Helper's inflammatory anti-slavery book in North Carolina |
| US/the World |
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Queen Isabella of Spain approves the preliminary terms of a punitive treaty against Morocco |
| US/the World |
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First Japanese diplomatic mission to the United States arrives in California |
| Personal |
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Last survivor of the 1778 Wyoming Massacre dies in Ohio |
| Crime/Disasters |
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Kentucky Military Institute partially destroyed by fire |
| US/the World |
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The first Japanese diplomatic mission to the United States hosted in San Francisco |
| Foreign |
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King Victor-Emmanuel of Piedmont-Sardinia explains the transfer of Nice and Savoy to France |