| Business/Industry |
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The first east to west run of the Pony Express arrives at Carson City, Nevada |
| Education/Culture |
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Statue of Henry Clay inaugurated with great ceremony in Capitol Square, Richmond, Virginia |
| Campaigns/Elections |
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Indiana's Constitutional Union Party selects Ohio's Judge John McLean as choice for President |
| Business/Industry |
|
J. W. Richardson rides into St. Joseph, Missouri ending the first west to east run of the Pony Express |
| Campaigns/Elections |
|
In Virginia, Prince William County Republicans meet to choose delegates for the state convention in Wheeling |
| Campaigns/Elections |
|
Harrisburg, Pennsylvania elects Democrat William H. Kepner as its first mayor |
| Religion/Philosophy |
|
Passover ends |
| Crime/Disasters |
|
San Francisco lumber vessel sunk off the Oregon coast with all hands |
| Crime/Disasters |
|
In South Carolina, fire badly damages the Spartanburg Female College but no injuries are reported |
| US/the World |
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|
Inhabitants of Nice voting in a plebiscite on whether their district will become part of France |
| Crime/Disasters |
|
A California legislator shot and stabbed by a lobbyist on the floor of the Assembly dies of his wounds |
| US/the World |
|
Victor Emmanuel II receives a hero's welcome in Florence, the capital of his new province of Tuscany |
| Crime/Disasters |
|
Tornado strikes the town of Carlinville in west central Illinois but no deaths are reported |
| Lawmaking/Litigating |
|
New York requires fire escapes on city tenement buildings |
| Cultural |
|
Boxer John C. Heenan, "the Benicia Boy," and British champion Tom Sayers fight for a "world championship" |
| Crime/Disasters |
|
Oil well fire in Pennsylvania kills nineteen people |
| Campaigns/Elections |
|
New York State Republican Convention selects William H. Seward as its choice for President |
| Crime/Disasters |
|
Former Kansas governor challenges Attorney General of the United States to a duel |
| Religion/Philosophy |
|
Anti-Liquor agitation heats up in Minneapolis, Minnesota |
| Education/Culture |
|
In Boston, Henry Longfellow completes his famous poem, "Paul Revere's Ride" |
| Business/Industry |
|
In London, a chief cashier admits to a million dollar embezzlement of his bank |
| US/the World |
|
In Spain, commander of the recent abortive Carlist uprising executed by firing squad |
| Crime/Disasters |
|
In Topeka, Kansas, John Ritchie shoots and kills U.S. Marshal Leonard Arms during attempted arrest |
| US/the World |
|
In Italy, the Archbishop of Florence publicly blesses recently excommunicated King Victor Emmanuel II |
| Business/Industry |
|
The Charleston and Savannah Railroad begins service |
| Crime/Disasters |
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|
Earthquake and aftershocks strike Peru in the vicinity of the capital Lima |
| Foreign |
|
British and French forces occupy the strategic Chinese island of Chusan |
| Crime/Disasters |
|
Fire destroys the business district of Kenosha, Wisconsin |
| US/the World |
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Explorer John McDouall Stuart reaches the center of the Australian Continent |
| US/the World |
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In Italy, the inhabitants of Savoy vote in a plebiscite on whether their province will become part of France |
